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Immunoassay, Different Way to Detect COVID-19

By Eskanisa R

25 August 2020

Immunoassays are quick and accurate tests to detect COVID-19.

Photo source: Pixabay
In early August, an Instagram user @IndiraDiandra conducted COVID-19 test use different method, immunoassay. It emerged on the internet as ‘unusual’ way to detect COVID-19. What is immunoassay? Is there are differences between rapid test, swab test, and this method? Here is a brief explanation we collected from vary resources.
Immunoassays are quick and accurate tests that have the ability to capture, detect, and measure the specific target (antibodies) within five hours. Similar to rapid test, immunoassay using (blood) serum to check the antibodies qualitatively against SARS-CoV-2 which caused COVID-19.
As Kompas reported, American Chemical Society (ACS) Analytical Chemistry explained this method (test) more accurate and quick to detect antibodies in blood where the potential for cross-reactivity smaller than rapid test.
This method (test) also using a lateral flow immunoassay (LFA) technology—similar to pregnancy test where medical staffs using nitrocellulose membrane and typically antibodies to produce results. When a sample (blood) is added, the sample will flow along the test device passing through the conjugate pad into the nitrocellulose membrane onto absorbent pad.
Researchers also said immunoassays help detect negative diagnosis, monitoring patient recovery, and identify recovered individuals with high antibodies level. If after the test you get non-reactive results then there are three possibilities; not exposed, have been exposed to the virus but antibodies cannot detect (incubation period), and immune problems.
For those recently start working from office or meet others, can consider to take this test at any health care institution provide immunoassays. Ensure to applying health protocols wherever you are.

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